Water-dispersible vitamin-containing composition and cosmetic including the same



Patented Jan. 6, 1942 WATER-DISPERSIBLE VITAMIN-CONTAIN- ING COMPOSITION AND- COSMETIC IN- CLUDING THE SAME Loran 0. Buxton. Harrison. and Louis '1. Rosenberg, Bidgefleld Park, N. 1., minors to National Oil Products Company, Harrison, N. 3., a corporation of New Jersey I No Drawing. Application January 21, 1939, Serial No. 252,072

13 Claims.

This invention relates to a new composition of matter. In one of its specific aspects, the invention is directed to vitamin-containing externally applicable substances and especially to water-dispersible compositions containing vitamins A or D and to correlated improvements in the preparation of such compositions, and the externally applicable substances may be cosmetics, salves, ointments, rubs and other liquids, creams, pastes and solids which are applied externally to the human or animal body for a wide variety of purposes, such as healing, soothing, beautifying and the like.

Another object of the invention is to provide a water-dispersible vitamin-containing composition.

Another object of the invention is to provide an externally applicable substance containing fat-soluble vitamins therein.

Another object of the invention is to provide a highly stable vitamin-containing cosmetic.

Other objects of the invention will in part be obvious and will in part appear hereinafter.

According to the invention, a soap is prepared by reacting a fatty acid and a morpholine compound. An appropriate quantity of the desired notes a fatty acid residue and R denotes a hydrogen atom or an alkyl, aryl or alkaryl group:

And, it has been found that the morpholine compound which is preferably employed is morpholine or phenylmorpholine. The soap is preferably prepared by reacting a quantity of desired fatty acid with a stoichiometric quantity of the morpholine compound to produce an acid-free soap whose pH is 6.9 to 7.0.

The compositions of this invention essentially comprise a material rich in fat-soluble vitamins such as vitamins A and/or D, and this substance may be fish oil, fish liver oil, concentrates thereof, irradiated ergosterol preferably dissolved in an oil such as corn oil or the like, and other well known vitamin rich materials, together with the above neutral soap of the fatty acid and the morpholine compound. The soap preferably employed is the oleate of morpholine and is formed vitamin is added to the soap and may be dissolved therein. This vitamin-soap solution may be added directly to an externally applicable substance and dispersed therein by agitation. It is also within the purview of the invention to incorporate said vitamin-soap solution in the components of said substance in the course of preparing said substance.

The invention accordingly comprises the several steps and the relation of one or more of such steps with respect to each of the others, and the composition possessing the features, properties and the relation of constituents, which are exemplified in the following detailed disclosure, and the scope of the invention will be indicated in the claims.

The soap employed in accordance with this invention may be prepared by reacting a fatty acid and a morpholine compound. The reaction may be carried out with or without the aid of external heat. The fatty acid usedmay be either saturated or unsaturated and may contain any number of carbon atoms. Among others, found to be especially suitable, are oleic, stearic, linoleic, linolenic, palmitic, ricinoleic, lauric and myristic acids. If the fatty acid is normally solid, it is first melted before the morpholine compound is added thereto. The reaction which is norby adding morpholine and oleic acid in the following ratio: 14.7 parts of morpholine to 50 parts of oleic acid. The mixture is stirred until the mass is free from free fatty acid. The quantity of vitaminiferous material added to this soap is a matter of choice. After the addition, the soap-vitaminiferous material admixture is stirred until there is a solution formed'of the vitaminiferous material in said soap. The solution may be readily dispersed in water to providev a stable dispersion which may be kept indefinitely, provided the same is kept in a closed container. The morpholine oleate soap-Nitaminiferous material solution may be added directly to any desired externally applicable substance. This substance may be one of the cosmetics, such as shampoos, face tonic, hair tonics, hand lotions, face creams, vanishing cream and the like which usually contain a mucilaginous and/or an oleaginous material. It may also be any one of a wide variety of other externally applicable substances, such as salves, ointments,

rubs and the like. Among others, said solution may be added directly to those substances of the cosmetic species known to the trade as "J ergens Lotion, Italian Balm, Frostilla, Wood burys Cream without changing either the color,

- the texture or odor of the same. After adding many exothermic is as follows wherein R dethe appropriate quantity of said solution to the desired substance which may be of an aqueous or oily'base, the mass is agitated by stirring to distribute said solution uniformly throughout said substance. The morpholine oleate-vitaminiferous solution is thus emulsified in said substance and is uniformly blended with the constituents thereof and is uniformly distributed throughout the substance as very fine'particles or globules which will not settle out, the morpholine oleate acting as the emulsifier for said vitaminiferous material in said substance. The addition of the morpholine oleate soap-vitaminiferous material solution does not appreciably alter the physical or chemical characteristics of said substance, and as a matter of fact, does not in anyway deleteriously affect the same. Instead of adding the morpholine oleate-vitaminiferous solution to the finished substance, said solution may be added to the components thereof in the course of preparing the same.

For a fuller understanding of the nature and objects of the invention, reference should be had to the following examples which are given merely to further illustrate the invention and are not to be construed in a limiting sense, all parts given being by weight:

Example I 282 grams of oleic acid are mixed with 87 grams of morpholine to produce 369 parts of morpholine oleate. To each 100 grams of said morpholine cleate add between 4 and 5 grams of vitamin D tuna fish liver oil concentrate, whose potency is 1,000,000 units of vitamin D per gram. The mixture is stirred to produce a clear solution of vitamin D-concentrate in morpholine oleate. This solution is added to a batch of finished hand lotion comprising an emulsion of an oily or waxy material in water, and sold under the name of Jergens Lotion which measures between 400 to 4,000 grams and the entire mass is stirreduntil the solution is emulsified in said cosmetic, uniformly blended therewith and uniformly distributed as very fine particles or globules throughout said cosmetic which now contains between 10,000 to 1,000 units of vitamin D per gram thereof.

Example 11 282 grams of oleic acid are mixed with 87 grams of morpholine to produce 369 grams of morpholine oleate. To each 100 grams of said morpholine oleate, add between 8 to 10 grams of a concentrate whose potency is 500,000 units of vitamin A and 100,000 units of vitamin D per gram. The mixture is stirred to producea clear solution of the concentrate in morpholine oleate. This solution is added to a batch of finished cream comprising a water-in-oil emulsion, the oily phase containing materials of. an oily or waxy nature, and sold under the name of Woodburys All Purpose Cream, varying from 400 to 4,000 grams and the entire mass is stirred until the solution is emulsified in said cosmetic, uniformly blended with the constituents thereof and uniformly distributed as very fine particles or globules throughout said cosmetic which now contains between 10,000 and 1,000 units of vitamin A and between 2,000 and 200 units of vitamin D.

Since certain changes in carrying out the above process and certain modifications in the composition which embody the invention may be made without departing from its scope, it is intended that all matter contained in the above description shall be interpreted as illustrative and not in a limiting sense.

It is also to be understood that the following claims are intended to cover allthe generic and specific features of the invention herein described and all statements of the scope of the invention, which as a matter of language might be said to fall therebetween; and that they are intended to be inclusive in scope and notexclusive, in that if desired other materials may be added to our novel composition of matter herein claimed without departing from the spirit of the invention. Particularly it is to be understood that in said claims, ingredients or components recited in the singular are intended to include compatible mixtures of said ingredients wherever the sense permits.

Having described our invention, what weclaim as new and desire to secure by Letters Patent is:

1. A readily emulsifiable composition comprising a soap of a higher fatty acid and a morpholine compound and a vitamin A and D concentrate.

2. A readily emulsifiable composition comprising a morpholine soap of a higher fatty acid and a vitamin A concentrate.

3. A readily emulsifiable composition comprising a morpholine soap oi' a higher fatty acid and a vitamin D concentrate.

4. A readily emulsiflable composition comprising a morpholine soap of a higher fatty acid and a vitamin A and D concentrate.

5. A readily emulsifiable composition comprising morpholine oleate and a vitamin A and D concentrate.

6. A readily emulslfiable composition comprising morpholine ricinoleate and a vitamin A and D concentrate.

7. A readily emulsifiable composition comprising morpholine linolenate and a vitamin A and D concentrate.

8. A cosmetic emulsion comprising a substance selected from the class consisting of mucilaginous and oleaginous materials, a morpholine soap of a higher fatty acid and a vitamin A concentrate.

9. A cosmetic emulsion comprising a substance selected from the class consisting of mucilaginous and oleaginous materials, a morpholine soap of a higher fatty acid and a vitamin D concentrate.

10. A cosmetic emulsion comprising a substance selected from the class consisting of mucilaginous and oleaginous materials, a morpholine soap of a higher fatty acid and a vitamin A and D concentrate.

11. A cosmetic emulsion comprising a substance selected from the class consisting of mucilaginous and oleaginous materials, morpholine oleate, and a vitamin.A and D concentrate.

12. A cosmetic emulsion comprising a substance selected from the class consisting of mucilaginous and oleaginou's materials, morpholine ricinoleate. and a vitamin A and D concentrate.

13. A cosmetic emulsion comprising a substance selected from the class consisting of mucilaginous and oleagincus materials, morpholine linolenate. and a vitamin A and D concentrate.

LORAN o. BUXTON. LOUIS 'r. ROSENBERG 

